The development of high throughput technologies has given rise to a wealth of information at system level including genome, transcriptome, proteome and metabolome. However, it remains a major challenge to digest the massive amounts of information and use it in an intelligent and comprehensive manner. To address this question, Dr. Fei’s group has focused on developing computational tools and resources to analyze and integrate large scale "omics" datasets", which help researchers to understand how genes work together to comprise functioning cells and organisms..
Itaya A, Bundschuh R, Archual A, Joung J, Fei Z, Dai X, Zhao P, Tang Y, Nelson R, and Ding B. 2008. Small RNAs in tomato fruit and leaf development. BBA - Gene Regulatory Mechanisms 1779: 99-107
Ouyang, B., T. Yang, H. Li, L. Zhang, Y. Zhang, J. Zhang, Z. Fei, Z. Ye. 2007. Identification of salt stress regulated genes in tomato seedlings by suppression subtracted hybridization and microarray analysis . Journal of Experimental Botany 58: 507-520
Dan, Y, Fei Z, and Rothan, C. 2007. MicroTom – A New Model System for Plant Genomics. Genes, Genomes and Genomics 1: 167-179
Gilchrist, C., E. Houpt, N. Trapaidze, Z. Fei, O. Crasta, A. Asgharpour, C. Evans, C. Martino-Catt, D. Baba, S. Stroup, S. Hamano, G. Ehrenkaufer, O. Okada, U. Singh, T. Nozaki, B. Mann, W. Petri Jr.. 2006. Impact of intestinal colonization and invasion on the E. histolytica transcriptome. Mol Biochem Parasitol 147: 163-176